Use At Any Time Of The Day And As Often As Necessary1 - Massage A Small Amount Onto The Backs And Palms Of Your Hands With Large Circular Motions. 2 Minutes Of Gentle Massage Will Allow The Cream To Penetrate The Upper Layers Of Your Skin For Immediate Comfort2 - Take Time To Work The Formula Into Your Fingers, Over Your Knuckles, And On The Dry Areas Between Your Fingers3 - With Any Remaining Cream, Massage Into Each Finger, From The Top Of The Knuckle Down To The Ends Of Your Fingertips? .